A 74-year-old with persistent diarrhea after antibiotics has leukocytosis and positive C. difficile toxin. He had CDI 3 months ago treated with vancom...

Question

A 74-year-old with persistent diarrhea after antibiotics has leukocytosis and positive C. difficile toxin. He had CDI 3 months ago treated with vancomycin. Best therapy now?

Accepted Answer

Fidaxomicin is preferred for recurrence; consider bezlotoxumab adjunct in high‑risk

Answer

Metronidazole alone

Answer

No therapy; spontaneous resolution is expected

Answer

Probiotics only

Answer

Prolonged IV vancomycin

us-abim MCQ (SBA): Recurrent CDI

A 74-year-old with persistent diarrhea after antibiotics has leukocytosis and positive C. difficile toxin. He had CDI 3 months ago treated with vancomycin. Best therapy now?