Question

A 59-year-old with diabetes and CKD G4 (eGFR 25) asks whether to continue SGLT2 inhibitor. He is euvolemic. Albuminuria 900 mg/g. What do guidelines advise?

Accepted Answer

Continue SGLT2 inhibitor down to eGFR ≥20 mL/min/1.73 m² for kidney/CV benefit if tolerated

Answer

Stop SGLT2 inhibitor when eGFR <45

Answer

Stop all RAS blockade at eGFR 25

Answer

Start dual RAS blockade

Answer

SGLT2 inhibitors have no benefit without diabetes

Practice question

A 59-year-old with diabetes and CKD G4 (eGFR 25) asks whether to continue SGLT2 inhibitor. He is euvolemic. Albuminuria 900 mg/g. What do guidelines advise?