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MediumHR ≥70 bpm on maximally tolerated beta-blocker to reduce HF hospitalization. Non-DHP CCBs (verapamil/diltiazem) are harmful in HFrEF. Digoxin does not primarily target HR and is not first to reduce hospitalizations. Amiodarone is for arrhythmia controlAHA/ACC/HFSA Guideline (2022): Management of Heart Failurecardiology

A 61-year-old man with HFrEF (EF 25%) and sinus rhythm has resting HR 82 bpm on max tolerated beta-blocker. Which additional rate-targeting drug may reduce HF hospitalization if criteria met?

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