A 68-year-old man with NSTEMI has LDL 130 mg/dL. He asks about PCSK9 inhibitors before trying ezetimibe. What is recommended?...

Question

A 68-year-old man with NSTEMI has LDL 130 mg/dL. He asks about PCSK9 inhibitors before trying ezetimibe. What is recommended?

Accepted Answer

Add ezetimibe to maximally tolerated statin before PCSK9; escalate if LDL ≥70 persists

Answer

PCSK9 is first-line after statin in all

Answer

Stop statin and use PCSK9 monotherapy

Answer

No further LDL lowering needed

Answer

Niacin is preferred next step

us-abim MCQ (SBA): Sequence of Nonstatin Therapy