Question

A 72-year-old with nonvalvular atrial fibrillation (paroxysmal) has CHA₂DS₂‑VASc = 3 (age ≥65, hypertension, diabetes). Creatinine clearance is 60 mL/min. Which is the most appropriate long‑term stroke‑prevention strategy?

Accepted Answer

Apixaban 5 mg twice daily

Answer

Warfarin with INR target 1.5-2.0

Answer

Aspirin 81 mg daily alone

Answer

Clopidogrel 75 mg daily plus aspirin 81 mg daily

Answer

No antithrombotic therapy needed for paroxysmal AF

Practice question

A 72-year-old with nonvalvular atrial fibrillation (paroxysmal) has CHA₂DS₂‑VASc = 3 (age ≥65, hypertension, diabetes). Creatinine clearance is 60 mL/min. Which is the most appropriate long‑term stroke‑prevention strategy?