Question

A 60-year-old with HFrEF (LVEF 25%) NYHA II, no hyperkalemia, eGFR 45 mL/min/1.73 m², is newly diagnosed and not on heart-failure therapy. Which foundational regimen reflects current guideline-directed medical therapy (GDMT)?

Accepted Answer

ARNI + evidence-based beta-blocker + MRA + SGLT2 inhibitor

Answer

ACE inhibitor + any beta-blocker + loop diuretic

Answer

ARB + ivabradine + loop diuretic

Answer

Hydralazine/isosorbide dinitrate monotherapy

Answer

ACE inhibitor + thiazide diuretic + digoxin

Practice question

A 60-year-old with HFrEF (LVEF 25%) NYHA II, no hyperkalemia, eGFR 45 mL/min/1.73 m², is newly diagnosed and not on heart-failure therapy. Which foundational regimen reflects current guideline-directed medical therapy (GDMT)?