Question

A 72-year-old on apixaban 5 mg BID for AF will undergo elective colon cancer resection (high bleeding risk). Renal function normal. Perioperative anticoagulation plan?

Accepted Answer

Stop apixaban 48 hours before surgery; no heparin bridge

Answer

Continue apixaban through surgery

Answer

Stop apixaban 24 hours before surgery; no bridge

Answer

Stop apixaban 5 days prior and bridge with LMWH

Answer

Switch to warfarin now and bridge pre-op

Practice question

A 72-year-old on apixaban 5 mg BID for AF will undergo elective colon cancer resection (high bleeding risk). Renal function normal. Perioperative anticoagulation plan?