A 78-year-old on warfarin presents with spontaneous intracranial hemorrhage (INR 3.4) and focal deficits. What is the best reversal strategy?...

Question

A 78-year-old on warfarin presents with spontaneous intracranial hemorrhage (INR 3.4) and focal deficits. What is the best reversal strategy?

Accepted Answer

4-factor PCC plus IV vitamin K

Answer

Stop warfarin and observe; no reversal needed

Answer

Vitamin K 10 mg orally only

Answer

Fresh frozen plasma alone

Answer

Protamine sulfate

us-usmle-step-2 MCQ (SBA): Anticoagulant Reversal