Question

A 55-year-old with recurrent gout flares and tophus at the olecranon has stage 3 CKD. Serum urate is 9.0 mg/dL. Which is the preferred urate-lowering therapy to initiate?

Accepted Answer

Allopurinol (titrate to serum urate <6 mg/dL)

Answer

Probenecid

Answer

Febuxostat first-line

Answer

Pegloticase

Answer

No ULT; use NSAIDs only

Practice question

A 55-year-old with recurrent gout flares and tophus at the olecranon has stage 3 CKD. Serum urate is 9.0 mg/dL. Which is the preferred urate-lowering therapy to initiate?