Question

A 68-year-old man with paroxysmal atrial fibrillation (nonvalvular), hypertension, and type 2 diabetes has an eGFR of 75 mL/min/1.73 m² and no prior bleeding. His CHA₂DS₂-VASc score is 3. What is the most appropriate long-term strategy to prevent stroke?

Accepted Answer

Start a direct oral anticoagulant (e.g., apixaban)

Answer

Begin aspirin 81 mg daily

Answer

No antithrombotic therapy

Answer

Warfarin with INR target 2-3 as first-line

Answer

Left atrial appendage occlusion now

Practice question

A 68-year-old man with paroxysmal atrial fibrillation (nonvalvular), hypertension, and type 2 diabetes has an eGFR of 75 mL/min/1.73 m² and no prior bleeding. His CHA₂DS₂-VASc score is 3. What is the most appropriate long-term strategy to prevent stroke?