A 66-year-old with COPD (FEV₁ 48% predicted), 3 moderate exacerbations last year, and blood eosinophils 350/µL has dyspnoea despite LAMA. What is the ...

Question

A 66-year-old with COPD (FEV₁ 48% predicted), 3 moderate exacerbations last year, and blood eosinophils 350/µL has dyspnoea despite LAMA. What is the preferred initial/next pharmacologic regimen?

Accepted Answer

Start triple therapy with ICS/LABA/LAMA

Answer

SABA as needed only

Answer

Escalate to LAMA monotherapy at higher dose

Answer

LABA/LAMA dual therapy only

Answer

Roflumilast monotherapy

us-abfm MCQ (SBA): COPD Exacerbation Prevention

A 66-year-old with COPD (FEV₁ 48% predicted), 3 moderate exacerbations last year, and blood eosinophils 350/µL has dyspnoea despite LAMA. What is the preferred initial/next pharmacologic regimen?