Question

A 62-year-old hospitalized with first episode, non-severe C. difficile infection (WBC 12,000/µL; creatinine 1.0 mg/dL) asks about therapy. Best initial treatment?

Accepted Answer

Fidaxomicin 200 mg orally twice daily for 10 days

Answer

Metronidazole 500 mg orally three times daily for 10 days

Answer

Vancomycin 125 mg orally four times daily plus IV metronidazole

Answer

Probiotics alone

Answer

Observation with hydration only

Practice question

A 62-year-old hospitalized with first episode, non-severe C. difficile infection (WBC 12,000/µL; creatinine 1.0 mg/dL) asks about therapy. Best initial treatment?