Question

A 60-year-old with newly diagnosed HFrEF (EF 30%) is euvolemic after diuresis. Which combination best represents guideline-directed medical therapy to reduce mortality?

Accepted Answer

ARNI + evidence-based beta-blocker + MRA + SGLT2 inhibitor

Answer

ACE inhibitor alone

Answer

Beta-blocker monotherapy

Answer

Nitrate plus hydralazine only

Answer

Loop diuretic plus thiazide chronically

Practice question

A 60-year-old with newly diagnosed HFrEF (EF 30%) is euvolemic after diuresis. Which combination best represents guideline-directed medical therapy to reduce mortality?