{"@context":"https://schema.org","@type":"Quiz","learningResourceType":"PracticeProblem","inLanguage":"en-GB","hasPart":[{"@type":"Question","eduQuestionType":"Multiple choice","text":"A 58-year-old with recurrent gout and tophus has SU 8.7 mg/dL. Which treat-to-target goal is recommended for urate-lowering therapy?","encodingFormat":"text/plain","suggestedAnswer":[{"@type":"Answer","text":"<7.5 mg/dL","encodingFormat":"text/plain","position":1},{"@type":"Answer","text":"<7 mg/dL for all; <8 mg/dL if tophaceous","encodingFormat":"text/plain","position":2},{"@type":"Answer","text":"<6 mg/dL (and <5 mg/dL if severe tophaceous disease)","encodingFormat":"text/plain","position":3},{"@type":"Answer","text":"Any reduction from baseline is adequate","encodingFormat":"text/plain","position":4},{"@type":"Answer","text":"<4 mg/dL for all patients","encodingFormat":"text/plain","position":5}],"educationalAlignment":[{"@type":"AlignmentObject","alignmentType":"educationalSubject","targetName":"us-abim"},{"@type":"AlignmentObject","alignmentType":"educationalSubject","targetName":"us-abfm"},{"@type":"AlignmentObject","alignmentType":"educationalSubject","targetName":"us-usmle-step-2"}],"acceptedAnswer":{"@type":"Answer","text":"<6 mg/dL (and <5 mg/dL if severe tophaceous disease)","encodingFormat":"text/plain","position":3,"answerExplanation":{"@type":"Comment","text":"ACR recommends ULT (allopurinol first-line) with a treat-to-target serum urate <6 mg/dL; a lower target (<5 mg/dL) may be used in tophaceous gout. Higher targets are insufficient; vague reductions lack evidence. [1]"}}}],"about":["us-abim","us-abfm","us-usmle-step-2","Rheumatology","Gout"],"name":"us abim rheumatology a 58 year old with recurrent gout and","isAccessibleForFree":true}

Practice question

A 58-year-old with recurrent gout and tophus has SU 8.7 mg/dL. Which treat-to-target goal is recommended for urate-lowering therapy?