Question

A 68-year-old on apixaban 5 mg twice daily for AF is scheduled for elective colectomy (high bleeding risk). Renal function is normal. How should anticoagulation be managed?

Accepted Answer

Hold apixaban 48-72 hours before surgery; no heparin bridging

Answer

Continue apixaban through surgery

Answer

Hold apixaban 24 hours before surgery; no bridging

Answer

Bridge with therapeutic LMWH for 3 days before surgery

Answer

Switch to warfarin 1 week prior

Practice question

A 68-year-old on apixaban 5 mg twice daily for AF is scheduled for elective colectomy (high bleeding risk). Renal function is normal. How should anticoagulation be managed?