Question

A 49-year-old with symptomatic hyperglycemia (polyuria, weight loss), fasting glucose 360 mg/dL, and A1C 11% seeks treatment. What is the best initial pharmacologic approach?

Accepted Answer

Initiate insulin therapy

Answer

Start metformin monotherapy

Answer

Start GLP-1 receptor agonist monotherapy

Answer

Start SGLT2 inhibitor monotherapy

Answer

No pharmacologic therapy; lifestyle only

Practice question

A 49-year-old with symptomatic hyperglycemia (polyuria, weight loss), fasting glucose 360 mg/dL, and A1C 11% seeks treatment. What is the best initial pharmacologic approach?