A 58-year-old on lisinopril for HFrEF develops an ACE inhibitor-induced cough. LVEF 28%, BP 118/72. What is the recommended disease-modifying substitu...

Question

A 58-year-old on lisinopril for HFrEF develops an ACE inhibitor-induced cough. LVEF 28%, BP 118/72. What is the recommended disease-modifying substitution?

Accepted Answer

Switch to sacubitril/valsartan with 36-hour ACE inhibitor washout

Answer

Switch to losartan now

Answer

Add hydralazine-isosorbide only

Answer

Continue ACE inhibitor and add digoxin

Answer

Start sacubitril/valsartan immediately without washout

us-usmle-step-1 MCQ (SBA): Heart Failure-ARNI Use

A 58-year-old on lisinopril for HFrEF develops an ACE inhibitor-induced cough. LVEF 28%, BP 118/72. What is the recommended disease-modifying substitution?