Question

A 45-year-old man of Han Chinese ancestry has recurrent gout flares (urate 9.2 mg/dL). Which initiation strategy for urate-lowering therapy is most appropriate?

Accepted Answer

Initiate allopurinol at low dose with HLA-B*58:01 testing prior to therapy

Answer

Start febuxostat and avoid HLA-B*58:01 testing

Answer

Avoid ULT until he is flare-free for 6 months

Answer

Begin probenecid as first-line in CKD stage 3

Answer

Start allopurinol only if tophi appear

Practice question

A 45-year-old man of Han Chinese ancestry has recurrent gout flares (urate 9.2 mg/dL). Which initiation strategy for urate-lowering therapy is most appropriate?