Question

A 63-year-old hospitalized with severe sepsis from pyelonephritis receives 2.5 L LR (80 kg) and broad-spectrum antibiotics. MAP remains 58 mm Hg. Best next step?

Accepted Answer

Start norepinephrine to target MAP ≥65 mm Hg.

Answer

Add vasopressin as first-line pressor.

Answer

Begin dopamine for renal perfusion.

Answer

Start epinephrine first.

Answer

Give 1 unit PRBCs to raise MAP.

Practice question

A 63-year-old hospitalized with severe sepsis from pyelonephritis receives 2.5 L LR (80 kg) and broad-spectrum antibiotics. MAP remains 58 mm Hg. Best next step?