Question

A 62-year-old with new HFrEF (LVEF 30%) is being discharged after decompensation. Blood pressure and renal function allow initiation of therapy. Which regimen reflects foundational guideline-directed medical therapy?

Accepted Answer

Sacubitril/valsartan, evidence-based beta-blocker, mineralocorticoid receptor antagonist, and an SGLT2 inhibitor.

Answer

ACE inhibitor plus any beta-blocker only.

Answer

Ivabradine and digoxin without beta-blocker.

Answer

Hydralazine/isosorbide mononitrate alone.

Answer

Loop diuretic and PRN nitrates only.

Practice question

A 62-year-old with new HFrEF (LVEF 30%) is being discharged after decompensation. Blood pressure and renal function allow initiation of therapy. Which regimen reflects foundational guideline-directed medical therapy?