Question

A 58-year-old with newly diagnosed HFrEF (LVEF 30%), NYHA II, normal renal function and potassium 4.4 mEq/L, is not on any HF medications. Which initial pharmacologic regimen most reduces mortality?

Accepted Answer

ARNI/ACEi-equivalent plus evidence-based beta-blocker plus MRA plus SGLT2 inhibitor

Answer

Loop diuretic monotherapy

Answer

ACE inhibitor alone

Answer

Digoxin plus loop diuretic

Answer

Hydralazine-isosorbide dinitrate alone

Practice question

A 58-year-old with newly diagnosed HFrEF (LVEF 30%), NYHA II, normal renal function and potassium 4.4 mEq/L, is not on any HF medications. Which initial pharmacologic regimen most reduces mortality?