A 48-year-old with gout has two flares in the past year and serum urate 9.2 mg/dL, normal renal function. Best long-term management?...

Question

A 48-year-old with gout has two flares in the past year and serum urate 9.2 mg/dL, normal renal function. Best long-term management?

Accepted Answer

Initiate allopurinol, titrate to serum urate

Answer

Start probenecid only during flares

Answer

Indefinite colchicine 0.6 mg daily without urate-lowering

Answer

Advise diet only; avoid medications

Answer

Start febuxostat only if allopurinol contraindicated, but no target

us-usmle-step-2 MCQ (SBA): Gout-urate-lowering therapy