Question

A 31-year-old with a painless genital ulcer and positive RPR is diagnosed with primary syphilis. No penicillin allergy. Preferred treatment?

Accepted Answer

Benzathine penicillin G 2.4 million units IM once

Answer

Doxycycline 100 mg BID ×14 days

Answer

Penicillin V 500 mg QID ×10 days

Answer

Ceftriaxone 1 g IM once

Answer

Azithromycin 2 g PO once

Practice question

A 31-year-old with a painless genital ulcer and positive RPR is diagnosed with primary syphilis. No penicillin allergy. Preferred treatment?