Question

A 64-year-old with newly diagnosed HFrEF (LVEF 30%) is euvolemic after diuresis. Which combination represents guideline-directed medical therapy to reduce mortality?

Accepted Answer

Sacubitril/valsartan + metoprolol succinate + spironolactone + an SGLT2 inhibitor

Answer

ACE inhibitor + any β-blocker

Answer

Hydralazine/isosorbide mononitrate alone

Answer

Diltiazem + loop diuretic chronically

Answer

Ivabradine monotherapy

Practice question

A 64-year-old with newly diagnosed HFrEF (LVEF 30%) is euvolemic after diuresis. Which combination represents guideline-directed medical therapy to reduce mortality?