Question

A 72-year-old on apixaban 5 mg twice daily for AF is scheduled for elective colectomy (high bleeding risk). Creatinine clearance is 80 mL/min. How should his anticoagulant be managed?

Accepted Answer

Hold apixaban for 2 days pre-op and resume 48-72 hours post-op

Answer

Continue apixaban through surgery

Answer

Hold apixaban for 1 day pre-op

Answer

Hold apixaban for 2 days pre-op and resume 24 hours post-op

Answer

Bridge with therapeutic LMWH during interruption

Practice question

A 72-year-old on apixaban 5 mg twice daily for AF is scheduled for elective colectomy (high bleeding risk). Creatinine clearance is 80 mL/min. How should his anticoagulant be managed?