Question

A 76-year-old woman with paroxysmal atrial fibrillation (AF), hypertension, and type 2 diabetes (no valvular disease) asks about stroke prevention. CHA2DS2-VASc = 5. eGFR 65 mL/min/1.73m². What is the most appropriate first-line agent?

Accepted Answer

Apixaban 5 mg twice daily

Answer

Warfarin with target INR 2.0-3.0

Answer

Aspirin 75 mg daily

Answer

Clopidogrel 75 mg daily

Answer

Dabigatran 150 mg twice daily plus aspirin

Practice question

A 76-year-old woman with paroxysmal atrial fibrillation (AF), hypertension, and type 2 diabetes (no valvular disease) asks about stroke prevention. CHA2DS2-VASc = 5. eGFR 65 mL/min/1.73m². What is the most appropriate first-line agent?