Question

A 32-year-old woman presents with increasing thirst, polyuria, and fatigue. Her BMI is 28 kg/m². Blood tests show: Fasting glucose 14 mmol/L, HbA1c 85 mmol/mol (9.9%). Urine ketones are negative. Anti-GAD antibodies are positive. What is the most appropriate initial management?

Accepted Answer

Insulin therapy (e.g., basal-bolus regimen)

Answer

Metformin 500mg OD

Answer

Gliclazide 80mg OD

Answer

Diet and lifestyle modification only

Answer

SGLT2 inhibitor (e.g., Dapagliflozin)

Practice question

A 32-year-old woman presents with increasing thirst, polyuria, and fatigue. Her BMI is 28 kg/m². Blood tests show: Fasting glucose 14 mmol/L, HbA1c 85 mmol/mol (9.9%). Urine ketones are negative. Anti-GAD antibodies are positive. What is the most appropriate initial management?