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MediumCardiologyHeart Failure (HFrEF)ukmlamrcgp aktpanemrcem sbamrcp part 1prescribing safety assessment

A 72-year-old man presents with progressive shortness of breath on exertion and ankle swelling. On examination, he has bibasal fine inspiratory crackles, a displaced apex beat, and raised jugular venous pressure. Echocardiogram shows a left ventricular ejection fraction of 35%. What is the most appropriate initial combination of medications according to NICE guidelines?

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