Question

A 52-year-old man with depression started on sertraline 50 mg daily 3 days ago returns with acute agitation, sweating, tremor, diarrhoea, and hyperreflexia after taking St John's wort. Likely diagnosis?

Accepted Answer

Serotonin syndrome

Answer

SSRI discontinuation syndrome

Answer

Neuroleptic malignant syndrome

Answer

Anticholinergic toxicity

Answer

Opioid withdrawal

Practice question

A 52-year-old man with depression started on sertraline 50 mg daily 3 days ago returns with acute agitation, sweating, tremor, diarrhoea, and hyperreflexia after taking St John's wort. Likely diagnosis?