Question

A 74-year-old woman on apixaban for AF presents with ischaemic stroke symptoms within 2 hours. CT shows no haemorrhage. Regarding reperfusion therapy:

Accepted Answer

Thrombolysis contraindicated if recent DOAC ingestion; consider mechanical thrombectomy if eligible

Answer

Proceed with IV thrombolysis immediately

Answer

Wait 24 hours and thrombolyse

Answer

Give aspirin 300 mg then thrombolyse

Answer

Switch apixaban to warfarin and thrombolyse

Practice question

A 74-year-old woman on apixaban for AF presents with ischaemic stroke symptoms within 2 hours. CT shows no haemorrhage. Regarding reperfusion therapy: