A 72-year-old with AF on warfarin (INR 2.6) presents with upper GI bleed (melaena, Hb drop). He is haemodynamically stable after fluids. What is the m...

Question

A 72-year-old with AF on warfarin (INR 2.6) presents with upper GI bleed (melaena, Hb drop). He is haemodynamically stable after fluids. What is the most appropriate initial reversal strategy for anticoagulation?

Accepted Answer

4-factor prothrombin complex concentrate (PCC) plus IV vitamin K

Answer

Vitamin K IV alone

Answer

Fresh frozen plasma (FFP) alone

Answer

No reversal required with INR 2.6

Answer

Protamine sulfate

mrcp part 1 MCQ (SBA): Upper GI Bleed on Warfarin

A 72-year-old with AF on warfarin (INR 2.6) presents with upper GI bleed (melaena, Hb drop). He is haemodynamically stable after fluids. What is the most appropriate initial reversal strategy for anticoagulation?