Question

A 72-year-old man with permanent atrial fibrillation (CHA₂DS₂-VASc 4, eGFR 48 mL/min/1.73m²) requires stroke prevention. He is not on any anticoagulant. What is the most appropriate first-line option in primary care?

Accepted Answer

Apixaban standard dose 5 mg twice daily

Answer

Warfarin with target INR 2.5

Answer

Aspirin 75 mg daily

Answer

Dabigatran 150 mg twice daily

Answer

Apixaban reduced dose 2.5 mg twice daily

Practice question

A 72-year-old man with permanent atrial fibrillation (CHA₂DS₂-VASc 4, eGFR 48 mL/min/1.73m²) requires stroke prevention. He is not on any anticoagulant. What is the most appropriate first-line option in primary care?