Question

A 50-year-old woman presents with a 3-month history of fatigue, weight gain, and constipation. Examination reveals a palpable, non-tender goitre. Her TSH is 25 mU/L (0.4-4.0) and fT4 is 6 pmol/L (12-22). Which antibody test is most likely to be positive?

Accepted Answer

Anti-thyroid peroxidase (TPO) antibodies

Answer

TSH receptor antibodies (TRAb)

Answer

Anti-nuclear antibodies (ANA)

Answer

Anti-mitochondrial antibodies (AMA)

Answer

Anti-cyclic citrullinated peptide (CCP) antibodies

Practice question

A 50-year-old woman presents with a 3-month history of fatigue, weight gain, and constipation. Examination reveals a palpable, non-tender goitre. Her TSH is 25 mU/L (0.4-4.0) and fT4 is 6 pmol/L (12-22). Which antibody test is most likely to be positive?