Question

A 40-year-old woman presents with chronic diarrhoea, bloating, and fatigue. She is found to have a mild iron deficiency anaemia. Which serological test is recommended by NICE as the first choice for diagnosing Coeliac disease?

Accepted Answer

Anti-tissue transglutaminase antibodies (anti-TTG) IgA

Answer

Anti-endomysial antibodies (EMA)

Answer

Anti-gliadin antibodies (AGA)

Answer

Anti-tissue transglutaminase antibodies (anti-TTG) IgG

Answer

HLA-DQ2/DQ8 genotyping

Practice question

A 40-year-old woman presents with chronic diarrhoea, bloating, and fatigue. She is found to have a mild iron deficiency anaemia. Which serological test is recommended by NICE as the first choice for diagnosing Coeliac disease?