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MediumRespiratory MedicineAcute Severe Asthmaukmlamrcem sbamrcp part 1paneprescribing safety assessment

A 24-year-old man with known asthma presents to A&E with shortness of breath. His peak expiratory flow rate is 40% of predicted. He has already received back-to-back nebulised salbutamol and ipratropium bromide, and intravenous hydrocortisone. He remains tachypnoeic and distressed. What is the next most appropriate intervention?

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