Question

A 42-year-old woman presents with acanthosis nigricans and BMI 36 kg/m². Fasting glucose 6.4 mmol/L, HbA1c 47 mmol/mol. What is the most appropriate initial pharmacological therapy?

Accepted Answer

Start metformin with lifestyle measures

Answer

Start insulin

Answer

Start sulfonylurea

Answer

No pharmacological therapy until HbA1c >53

Answer

Start SGLT2 inhibitor first-line

Practice question

A 42-year-old woman presents with acanthosis nigricans and BMI 36 kg/m². Fasting glucose 6.4 mmol/L, HbA1c 47 mmol/mol. What is the most appropriate initial pharmacological therapy?