A 74-year-old man is stabilized on warfarin for atrial fibrillation (target INR 2.5). He is prescribed a 5-day course of amoxicillin for a dental absc...

Question

A 74-year-old man is stabilized on warfarin for atrial fibrillation (target INR 2.5). He is prescribed a 5-day course of amoxicillin for a dental abscess. What is the most appropriate action regarding his anticoagulation?

Accepted Answer

No action required, continue current warfarin dose

Answer

Stop warfarin for the duration of the antibiotic course

Answer

Reduce warfarin dose by 25% immediately

Answer

Check INR 3-5 days after starting amoxicillin

Answer

Switch to a Direct Oral Anticoagulant (DOAC) temporarily

ukmla MCQ (SBA): Drug Interactions (Warfarin)

A 74-year-old man is stabilized on warfarin for atrial fibrillation (target INR 2.5). He is prescribed a 5-day course of amoxicillin for a dental abscess. What is the most appropriate action regarding his anticoagulation?