A 28-year-old man presents with a 6-week history of low mood, anhedonia, poor sleep, and fatigue. He has no suicidal ideation. He has tried guided sel...

Question

A 28-year-old man presents with a 6-week history of low mood, anhedonia, poor sleep, and fatigue. He has no suicidal ideation. He has tried guided self-help (low-intensity psychological intervention) with minimal improvement. What is the most appropriate next step in management according to NICE guidelines?

Accepted Answer

Start Sertraline 50mg daily

Answer

Start Venlafaxine 75mg daily

Answer

Refer for high-intensity psychological therapy (e.g., CBT)

Answer

Start Mirtazapine 15mg nocte

Answer

Refer to secondary care psychiatry

ukmla MCQ (SBA): Depression