A 35-year-old man with schizophrenia, treated with Haloperidol, is brought to the ED with confusion, high fever (40.5°C), and generalized muscle rigid...

Question

A 35-year-old man with schizophrenia, treated with Haloperidol, is brought to the ED with confusion, high fever (40.5°C), and generalized muscle rigidity ('lead pipe rigidity'). His BP is labile and he is tachycardic. CK is markedly elevated. What is the most likely diagnosis?

Accepted Answer

Neuroleptic Malignant Syndrome (NMS)

Answer

Serotonin Syndrome

Answer

Acute dystonic reaction

Answer

Tardive dyskinesia

Answer

Malignant hyperthermia

mrcp part 1 MCQ (SBA): Neuroleptic Malignant Syndrome

A 35-year-old man with schizophrenia, treated with Haloperidol, is brought to the ED with confusion, high fever (40.5°C), and generalized muscle rigidity ('lead pipe rigidity'). His BP is labile and he is tachycardic. CK is markedly elevated. What is the most likely diagnosis?