Question

A 48-year-old man presents with resistant hypertension. Despite taking Amlodipine 10mg, Ramipril 10mg, and Indapamide 2.5mg, his BP is 160/95 mmHg. Blood tests reveal hypokalaemia (K+ 3.1 mmol/L). What is the most appropriate initial investigation for a suspected secondary cause?

Accepted Answer

Plasma aldosterone-to-renin ratio (ARR)

Answer

24-hour urinary cortisol

Answer

Plasma metanephrines

Answer

Renal artery doppler ultrasound

Answer

Low-dose dexamethasone suppression test

Practice question

A 48-year-old man presents with resistant hypertension. Despite taking Amlodipine 10mg, Ramipril 10mg, and Indapamide 2.5mg, his BP is 160/95 mmHg. Blood tests reveal hypokalaemia (K+ 3.1 mmol/L). What is the most appropriate initial investigation for a suspected secondary cause?