Question

A patient with Cushing's syndrome has elevated cortisol that does not suppress with high-dose dexamethasone. ACTH levels are undetectable. Where is the likely source of excess cortisol?

Accepted Answer

Adrenal adenoma

Answer

Pituitary adenoma

Answer

Ectopic ACTH production

Answer

Adrenal hyperplasia

Answer

Iatrogenic (exogenous steroids)

Practice question

A patient with Cushing's syndrome has elevated cortisol that does not suppress with high-dose dexamethasone. ACTH levels are undetectable. Where is the likely source of excess cortisol?