A 24-year-old primigravida at 28 weeks gestation presents with a 1-week history of generalised itching, particularly severe on her palms and soles, an...

Question

A 24-year-old primigravida at 28 weeks gestation presents with a 1-week history of generalised itching, particularly severe on her palms and soles, and worse at night. She has no rash. Liver function tests (LFTs) show elevated bile acids and a mildly raised ALT. What is the most likely diagnosis?

Accepted Answer

Intrahepatic cholestasis of pregnancy (ICP)

Answer

Polymorphic eruption of pregnancy (PEP)

Answer

Pemphigoid gestationis

Answer

Acute fatty liver of pregnancy

Answer

PUPPP (pruritic urticarial papules and plaques of pregnancy)

ukmla MCQ (SBA): Intrahepatic Cholestasis of Pregnancy

A 24-year-old primigravida at 28 weeks gestation presents with a 1-week history of generalised itching, particularly severe on her palms and soles, and worse at night. She has no rash. Liver function tests (LFTs) show elevated bile acids and a mildly raised ALT. What is the most likely diagnosis?