A 24-year-old man is started on citalopram 20mg daily for depression. He is also taking ibuprofen regularly for back pain. After 1 week, he reports fe...

Question

A 24-year-old man is started on citalopram 20mg daily for depression. He is also taking ibuprofen regularly for back pain. After 1 week, he reports feeling generally well but mentions he has noticed some bruising more easily. What is the most likely interaction causing this?

Accepted Answer

Synergistic antiplatelet effect of citalopram and ibuprofen

Answer

Citalopram inhibiting ibuprofen metabolism

Answer

Ibuprofen increasing citalopram absorption

Answer

Citalopram inducing thrombocytopenia

Answer

Ibuprofen causing vitamin K deficiency

prescribing safety assessment MCQ (SBA): SSRI-NSAID Interaction

A 24-year-old man is started on citalopram 20mg daily for depression. He is also taking ibuprofen regularly for back pain. After 1 week, he reports feeling generally well but mentions he has noticed some bruising more easily. What is the most likely interaction causing this?