Question

A 70-year-old man is diagnosed with Paget's disease of bone affecting his pelvis, causing significant pain. His serum alkaline phosphatase (ALP) is markedly elevated. According to NICE guidelines, what is the first-line pharmacological treatment for symptomatic Paget's disease?

Accepted Answer

Zoledronic acid infusion

Answer

Alendronic acid

Answer

Risedronate sodium

Answer

Calcitonin injection

Answer

Pamidronate infusion

Practice question

A 70-year-old man is diagnosed with Paget's disease of bone affecting his pelvis, causing significant pain. His serum alkaline phosphatase (ALP) is markedly elevated. According to NICE guidelines, what is the first-line pharmacological treatment for symptomatic Paget's disease?