Question

A patient taking long-term lithium therapy for bipolar disorder requires treatment for hypertension. Which antihypertensive class should be avoided due to a significant interaction that can increase lithium levels and risk of toxicity?

Accepted Answer

Thiazide diuretics (e.g., Bendroflumethiazide)

Answer

Beta-blockers (e.g., Atenolol)

Answer

Calcium channel blockers (e.g., Amlodipine)

Answer

ACE inhibitors (e.g., Ramipril)

Answer

Alpha-blockers (e.g., Doxazosin)

Practice question

A patient taking long-term lithium therapy for bipolar disorder requires treatment for hypertension. Which antihypertensive class should be avoided due to a significant interaction that can increase lithium levels and risk of toxicity?