Question

A 30-year-old primigravida woman presents at 32 weeks gestation with generalised itching, particularly severe on the palms and soles, worse at night. She denies rash. Liver function tests show elevated bile acids; ALT and AST are mildly raised. What is the most likely diagnosis?

Accepted Answer

Intrahepatic cholestasis of pregnancy (ICP)

Answer

Polymorphic eruption of pregnancy (PEP)

Answer

Pemphigoid gestationis

Answer

Acute fatty liver of pregnancy (AFLP)

Answer

Prurigo of pregnancy

Practice question

A 30-year-old primigravida woman presents at 32 weeks gestation with generalised itching, particularly severe on the palms and soles, worse at night. She denies rash. Liver function tests show elevated bile acids; ALT and AST are mildly raised. What is the most likely diagnosis?