Question

A 68-year-old woman with type 2 diabetes, hypertension, and CKD stage 3b (eGFR 40 ml/min/1.73m²) has an HbA1c of 78 mmol/mol despite taking metformin 1g BD and gliclazide 80mg BD. According to NICE NG28, what would be an appropriate third-line agent to add, considering her renal function?

Accepted Answer

Sitagliptin (DPP-4 inhibitor)

Answer

Empagliflozin (SGLT2 inhibitor)

Answer

Pioglitazone

Answer

Exenatide (GLP-1 mimetic)

Answer

Insulin detemir

Practice question

A 68-year-old woman with type 2 diabetes, hypertension, and CKD stage 3b (eGFR 40 ml/min/1.73m²) has an HbA1c of 78 mmol/mol despite taking metformin 1g BD and gliclazide 80mg BD. According to NICE NG28, what would be an appropriate third-line agent to add, considering her renal function?