Practice question

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MediumRheumatologyOsteoarthritis Analgesiaukmlamrcgp aktpaneprescribing safety assessment

A 58-year-old woman with rheumatoid arthritis, well-controlled on methotrexate 15mg weekly and folic acid 5mg weekly (taken on a different day), requires analgesia for osteoarthritis pain in her knee. She has mild CKD (eGFR 55 ml/min/1.73m²). According to NICE CG177, which analgesic is generally considered the safest initial option alongside paracetamol?

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