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HardRheumatologyMethotrexate Toxicitymrcgp aktmrcp part 1ukmlapaneprescribing safety assessment

A 60-year-old woman with rheumatoid arthritis, well-controlled on methotrexate 15mg weekly and folic acid 5mg weekly (taken on a different day), complains of increasing fatigue. Blood tests show: Hb 98 g/L, MCV 105 fL, Platelets 130 x 10$^9$/L, WCC 3.5 x 10$^9$/L. What is the most likely cause of these findings?

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