Question

A 58-year-old woman presents with a 3-month history of fatigue, intermittent abdominal pain, bloating, and loose stools. Blood tests show Hb 105 g/L, MCV 78 fL, Ferritin 10 $\mu$g/L. What investigation is most appropriate to screen for coeliac disease according to NICE NG20?

Accepted Answer

Total IgA and anti-tissue transglutaminase (tTG) IgA antibodies

Answer

Anti-endomysial antibodies (EMA) only

Answer

Faecal calprotectin

Answer

Colonoscopy with biopsies

Answer

Hydrogen breath test

Practice question

A 58-year-old woman presents with a 3-month history of fatigue, intermittent abdominal pain, bloating, and loose stools. Blood tests show Hb 105 g/L, MCV 78 fL, Ferritin 10 $\mu$g/L. What investigation is most appropriate to screen for coeliac disease according to NICE NG20?